Additional file 3: of Cytolytic activity correlates with the mutational burden and deregulated expression of immune checkpoints in colorectal cancer

Additional file 3: of Cytolytic activity correlates with the mutational burden and deregulated expression of immune checkpoints in colorectal cancer

Figure S3. Gene set variation analysis (GSVA) of known immune-related gene sets (e.g., BIOCARTA_CTL_PATHWAY; TCYTOTOXIC_PATHWAY; TCRA_PATHWAY; THELPER_PATHWAY; PD1_SIGNALING; PRODUCING_DENDRITIC_CELL) showed statistically significant increase in CRCs identified as CYT-high, based on the expression...

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Bibliographische Detailangaben
Hauptverfasser: Zaravinos, Apostolos, Constantinos Roufas, Nagara, Majdi, Moreno, Beatriz Lucas, Oblovatskaya, Maria, Efstathiades, Christodoulos, Dimopoulos, Christos, Ayiomamitis, Georgios
Format: Bild
Sprache:eng
Schlagworte:
Biochemistry
Biological Sciences not elsewhere classified
Cancer
FOS: Biological sciences
FOS: Clinical medicine
FOS: Health sciences
FOS: Mathematics
Genetics
Immunology
Infectious Diseases
Mathematical Sciences not elsewhere classified
Medicine
Microbiology
Molecular Biology
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Zusammenfassung:Figure S3. Gene set variation analysis (GSVA) of known immune-related gene sets (e.g., BIOCARTA_CTL_PATHWAY; TCYTOTOXIC_PATHWAY; TCRA_PATHWAY; THELPER_PATHWAY; PD1_SIGNALING; PRODUCING_DENDRITIC_CELL) showed statistically significant increase in CRCs identified as CYT-high, based on the expression of GZMA and PRF1. (JPG 1293 kb)
DOI:10.6084/m9.figshare.9698060