Freshly isolated CD11c APCs from the BAL, lung parenchyma, and the spleen were cultured for 48 h with LPS or mycobacterial antigens (Mtb-CF)

Culture supernatants were measured for TNF-α (A) and IL-12 (B) by ELISA. Results are representative of three independent experiments and are presented as mean ± SD. *p < 0.05 compared to the corresponding lung data. #p < 0.05 compared to the corresponding spleen data.Copyright information:Taken from "CD11c+ antigen presenting cells from the alveolar space, lung parenchyma and spleen differ in their phenotype and capabilities to activate naïve and antigen-primed T cells"http://www.biomedcentral.com/1471-2172/9/48BMC Immunology 2008;9():48-48.Published online 13 Aug 2008PMCID:PMC2527294.