Detection of new motifs in exons and introns that correlate with CNS regulated AS events

Motifs correlating with central nervous system (CNS) associated alternative splicing (AS) levels were detected in exon sequences (C1, A, C2) and intron sequences (I1, I2) using the SeedSearcher algorithm [41]. searches for motifs were performed in the individual exon and intron sequences, and in concatenations of intron/exon sequences. Motifs enriched in these locations, as indicated by lines with arrowheads, are correlated with either increased inclusion (yellow boxes), increased exclusion (blue boxes), or a change in inclusion (black boxes), respectively.Copyright information:Taken from "Functional coordination of alternative splicing in the mammalian central nervous system"http://genomebiology.com/2007/8/6/R108Genome Biology 2007;8(6):R108-R108.Published online 12 Jun 2007PMCID:PMC2394768.