Analysis of symmetrical region near the centromeric end of 15q to identify its likeliest arrangement in RP11

The region between the most proximal segments P ordered as in Figure 5 is indicated by the four rows of segments at the top. The first row, continuing to the third row, represents the upper RP11 haplotigs in Figure 5 and the second row, continuing to the fourth row, represents the lower haplotigs. T...

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Hauptverfasser: Makoff, Andrew J, Flomen, Rachel H
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Sprache:eng
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Zusammenfassung:The region between the most proximal segments P ordered as in Figure 5 is indicated by the four rows of segments at the top. The first row, continuing to the third row, represents the upper RP11 haplotigs in Figure 5 and the second row, continuing to the fourth row, represents the lower haplotigs. The RP11 haplotigs are shown below the segments with the non-RP11 clones shown further below. Nine slices of 5 to 30 kilobases (kb), shown by alternating red or blue lines, were investigated, with each box showing the number of single nucleotide mismatches between each pair of RP11 haplotigs and non-RP11 clones in the slice.Copyright information:Taken from "Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes"http://genomebiology.com/2007/8/6/R114Genome Biology 2007;8(6):R114-R114.Published online 15 Jun 2007PMCID:PMC2394762.
DOI:10.6084/m9.figshare.81165