Androgenic dependence of exophytic tumor growth in a transgenic mouse model of bladder cancer: a role for thrombospondin-1-6

assayed and quantified for TSP1 expression by western blot analysis. () Relative bladder TSP1 protein expression in wild-type vs. UPII-SV40T mice. Values are relative means ± SE. For each group, n = 3. p = 0.0326*. () Relative bladder TSP1 protein expression in UPII-SV40T mice sacrificed 2, 3, 7, and 17 days after castration. Intact relative expression = 1. Values are relative means ± SE. For each group, n = 3. p = 0.0154** vs. intact. () Western blot of intact (n = 3) vs. 17-day castrate (n = 3) whole bladders from UPII-SV40T mice. TSP1 immunoblots were quantified. GAPDH control blot verified equal loading. P values determined by paired, two-tailed, student's t-test.Copyright information:Taken from "Androgenic dependence of exophytic tumor growth in a transgenic mouse model of bladder cancer: a role for thrombospondin-1"http://www.biomedcentral.com/1471-2490/8/7BMC Urology 2008;8():7-7.Published online 23 Apr 2008PMCID:PMC2374790.