Zebrafish and are paralogous members of the bromodomain-ET (BET) family of transcriptional coregulators that show structural and expression divergence-9

Upported and predicted transcripts from chromosome 16 ENSDARG00000046087 locus from Ensembl and NCBI databases, and D) partial cDNA from NCBI database. Some schematics include 5'UTR and 3' UTR, with wider rectangles depicting protein-coding regions. Boxes show conserved domains: bromodomain (red box); nuclear localization signal (horizontal striped); ET domain (yellow box); in C, degenerate second bromodomain (orange box); in C, upstream TAP domain (light blue box); valine-, leucine-rich region (VL-rich box); arginine-, serine-rich region (RS-rich box); start and stop codons (thick vertical lines); in A, SNPs between zf626 and zf619 (thin vertical lines); in B, discontinuous region in zf69 cDNA with repetitive sequences at bases 921–1033 and 1259–1413 (gray box); conserved intron/exon junction for alternative splicing in -related transcripts (arrow). Two-exon region in cDNA found in scaf_NA1181 is underscored in D. Length of cDNAs in base pairs is given in parentheses.Copyright information:Taken from "Zebrafish and are paralogous members of the bromodomain-ET (BET) family of transcriptional coregulators that show structural and expression divergence"http://www.biomedcentral.com/1471-213X/8/39BMC Developmental Biology 2008;8():39-39.Published online 10 Apr 2008PMCID:PMC2373290.