Additional file 5: of Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression
Figure S3. a Relative cell viability of circAKT3- or vector-transfected BGC823 cells with CDDP treatment at the indicated concentrations for 48 h. b Colony-forming ability of BGC823 cells transfected with circAKT3 or vector in the absence (Vehicle) or presence of CDDP (1.5 μM) for 48 h. c The apopto...
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| creator | Huang, Xiaoxu Li, Zheng Zhang, Qiang Wang, Weizhi Li, Bowen Wang, Lu Xu, Zhipeng Zeng, Ailiang Zhang, Xing Zhang, Xuan He, Zhongyuan Li, Qiang Sun, Guangli Wang, Sen Li, Qing Wang, Linjun Zhang, Lu Xu, Hao Xu, Zekuan |
| description | Figure S3. a Relative cell viability of circAKT3- or vector-transfected BGC823 cells with CDDP treatment at the indicated concentrations for 48 h. b Colony-forming ability of BGC823 cells transfected with circAKT3 or vector in the absence (Vehicle) or presence of CDDP (1.5 μM) for 48 h. c The apoptosis rates of BGC823 cells transfected with circAKT3 or vector upon CDDP (1.5 μM) for 48 h by flow cytometry. d Immunofluorescence staining of γH2AX foci in BGC823 cells transfected with circAKT3 or vector at 2 h after CDDP treatment (1.5 μM). Scale bars, 10 μm. e Percentage of cells containing >10 γH2AX foci in BGC823 cells transfected with circAKT3 or vector at 0 to 8 h after CDDP treatment (1.5 μM) removal. The results are presented as the mean ± SEM. *P |
| doi_str_mv | 10.6084/m9.figshare.7929239 |
| format | Image |
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Scale bars, 10 μm. e Percentage of cells containing >10 γH2AX foci in BGC823 cells transfected with circAKT3 or vector at 0 to 8 h after CDDP treatment (1.5 μM) removal. The results are presented as the mean ± SEM. *P<0.05, **P<0.01, ***P<0.001. (TIF 3594 kb)</description><identifier>DOI: 10.6084/m9.figshare.7929239</identifier><language>eng</language><publisher>figshare</publisher><subject>Biochemistry ; Cancer ; Cell Biology ; Chemical Sciences not elsewhere classified ; Computational Biology ; FOS: Biological sciences ; FOS: Clinical medicine ; FOS: Health sciences ; Hematology ; Immunology ; Infectious Diseases ; Marine Biology ; Microbiology ; Molecular Biology ; Virology</subject><creationdate>2019</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780,1892</link.rule.ids><linktorsrc>$$Uhttps://commons.datacite.org/doi.org/10.6084/m9.figshare.7929239$$EView_record_in_DataCite.org$$FView_record_in_$$GDataCite.org$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Huang, Xiaoxu</creatorcontrib><creatorcontrib>Li, Zheng</creatorcontrib><creatorcontrib>Zhang, Qiang</creatorcontrib><creatorcontrib>Wang, Weizhi</creatorcontrib><creatorcontrib>Li, Bowen</creatorcontrib><creatorcontrib>Wang, Lu</creatorcontrib><creatorcontrib>Xu, Zhipeng</creatorcontrib><creatorcontrib>Zeng, Ailiang</creatorcontrib><creatorcontrib>Zhang, Xing</creatorcontrib><creatorcontrib>Zhang, Xuan</creatorcontrib><creatorcontrib>He, Zhongyuan</creatorcontrib><creatorcontrib>Li, Qiang</creatorcontrib><creatorcontrib>Sun, Guangli</creatorcontrib><creatorcontrib>Wang, Sen</creatorcontrib><creatorcontrib>Li, Qing</creatorcontrib><creatorcontrib>Wang, Linjun</creatorcontrib><creatorcontrib>Zhang, Lu</creatorcontrib><creatorcontrib>Xu, Hao</creatorcontrib><creatorcontrib>Xu, Zekuan</creatorcontrib><title>Additional file 5: of Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression</title><description>Figure S3. a Relative cell viability of circAKT3- or vector-transfected BGC823 cells with CDDP treatment at the indicated concentrations for 48 h. b Colony-forming ability of BGC823 cells transfected with circAKT3 or vector in the absence (Vehicle) or presence of CDDP (1.5 μM) for 48 h. c The apoptosis rates of BGC823 cells transfected with circAKT3 or vector upon CDDP (1.5 μM) for 48 h by flow cytometry. d Immunofluorescence staining of γH2AX foci in BGC823 cells transfected with circAKT3 or vector at 2 h after CDDP treatment (1.5 μM). Scale bars, 10 μm. e Percentage of cells containing >10 γH2AX foci in BGC823 cells transfected with circAKT3 or vector at 0 to 8 h after CDDP treatment (1.5 μM) removal. The results are presented as the mean ± SEM. *P<0.05, **P<0.01, ***P<0.001. (TIF 3594 kb)</description><subject>Biochemistry</subject><subject>Cancer</subject><subject>Cell Biology</subject><subject>Chemical Sciences not elsewhere classified</subject><subject>Computational Biology</subject><subject>FOS: Biological sciences</subject><subject>FOS: Clinical medicine</subject><subject>FOS: Health sciences</subject><subject>Hematology</subject><subject>Immunology</subject><subject>Infectious Diseases</subject><subject>Marine Biology</subject><subject>Microbiology</subject><subject>Molecular Biology</subject><subject>Virology</subject><fulltext>true</fulltext><rsrctype>image</rsrctype><creationdate>2019</creationdate><recordtype>image</recordtype><sourceid>PQ8</sourceid><recordid>eNqdj89KA0EMh-fiQdQn8JIX6LrbqdrxthSLUihl6X0Is9ltYP-RzAq9--BOpb6Ap_D7Qn7hM-axyLOXfL166l3WcKsnFMpe3dItrbs132Vdc-RxwA4a7gie32BsYMMS5g4Fqn0J5e5oYZ6E2oQiKRw-d7YqII5AwwmHQBBYp7TjAYSUNf7ClFrUKBwgXIDAFyP0XC0Ktwadp1Spmn7fm5sGO6WH67wzdvt-3HwsaowYOJKfhHuUsy9yf3HxvfN_Lv7qYv939QMCHFzm</recordid><startdate>20190331</startdate><enddate>20190331</enddate><creator>Huang, Xiaoxu</creator><creator>Li, Zheng</creator><creator>Zhang, Qiang</creator><creator>Wang, Weizhi</creator><creator>Li, Bowen</creator><creator>Wang, Lu</creator><creator>Xu, Zhipeng</creator><creator>Zeng, Ailiang</creator><creator>Zhang, Xing</creator><creator>Zhang, Xuan</creator><creator>He, Zhongyuan</creator><creator>Li, Qiang</creator><creator>Sun, Guangli</creator><creator>Wang, Sen</creator><creator>Li, Qing</creator><creator>Wang, Linjun</creator><creator>Zhang, Lu</creator><creator>Xu, Hao</creator><creator>Xu, Zekuan</creator><general>figshare</general><scope>DYCCY</scope><scope>PQ8</scope></search><sort><creationdate>20190331</creationdate><title>Additional file 5: of Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression</title><author>Huang, Xiaoxu ; 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Scale bars, 10 μm. e Percentage of cells containing >10 γH2AX foci in BGC823 cells transfected with circAKT3 or vector at 0 to 8 h after CDDP treatment (1.5 μM) removal. The results are presented as the mean ± SEM. *P<0.05, **P<0.01, ***P<0.001. (TIF 3594 kb)</abstract><pub>figshare</pub><doi>10.6084/m9.figshare.7929239</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Biochemistry Cancer Cell Biology Chemical Sciences not elsewhere classified Computational Biology FOS: Biological sciences FOS: Clinical medicine FOS: Health sciences Hematology Immunology Infectious Diseases Marine Biology Microbiology Molecular Biology Virology |
| title | Additional file 5: of Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression |
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