Additional file 5: of Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression

Figure S3. a Relative cell viability of circAKT3- or vector-transfected BGC823 cells with CDDP treatment at the indicated concentrations for 48 h. b Colony-forming ability of BGC823 cells transfected with circAKT3 or vector in the absence (Vehicle) or presence of CDDP (1.5 μM) for 48 h. c The apoptosis rates of BGC823 cells transfected with circAKT3 or vector upon CDDP (1.5 μM) for 48 h by flow cytometry. d Immunofluorescence staining of γH2AX foci in BGC823 cells transfected with circAKT3 or vector at 2 h after CDDP treatment (1.5 μM). Scale bars, 10 μm. e Percentage of cells containing >10 γH2AX foci in BGC823 cells transfected with circAKT3 or vector at 0 to 8 h after CDDP treatment (1.5 μM) removal. The results are presented as the mean ± SEM. *P