Polymorphisms affect expression levels of plasminogen activator inhibitor type 1 in cultured fibroblasts-2

RNA against messenger (B), or with a scrambled RNA as control (A). PAI-1 inducers (TNFα, TGFβ, or insulin) were added 24 hours post-transfection and and expression was evaluated by semiquantitative RT-PCR 24 hours after agonist challenge. Normalized values of mRNA were grouped as mean ± standard error of arbitrary units. ANOVA was used to test differences across treatments (control, scrambled and iRNA). * Significant differences compared with scrambled by Tukey test; P < 0.05 and ** P < 0.01.Copyright information:Taken from "polymorphisms affect expression levels of plasminogen activator inhibitor type 1 in cultured fibroblasts"http://www.biomedcentral.com/1471-2261/8/5BMC Cardiovascular Disorders 2008;8():5-5.Published online 29 Feb 2008PMCID:PMC2292137.