Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density-3

Bsequently added to C8166 T-cells. Alternatively, T-cells were pretreated with AMD3100, enfuvirtide, or efavirenz for 15 min. Virion fusion was analyzed by multiparameter flow cytometry as reported [17, 29]. Shown are representative FACS dot plots for the detection of CCF2 substrate cleavage. (B) A...

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Hauptverfasser: Geuenich, Silvia, Goffinet, Christine, Venzke, Stephanie, Nolkemper, Silke, Baumann, Ingo, Plinkert, Peter, Reichling, Jürgen, Keppler, Oliver T
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Sprache:eng
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Zusammenfassung:Bsequently added to C8166 T-cells. Alternatively, T-cells were pretreated with AMD3100, enfuvirtide, or efavirenz for 15 min. Virion fusion was analyzed by multiparameter flow cytometry as reported [17, 29]. Shown are representative FACS dot plots for the detection of CCF2 substrate cleavage. (B) A replication assay with an experimental set-up analogous to that described in the legend to Fig. 1 was performed with the identical virus stock used in the virion-fusion assay. (C) MTT viability assay. Each experiment was performed in triplicate, and four independent experiments were conducted. Given are arithmetic means ± SD from one experiment.Copyright information:Taken from "Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density"http://www.retrovirology.com/content/5/1/27Retrovirology 2008;5():27-27.Published online 20 Mar 2008PMCID:PMC2288616.
DOI:10.6084/m9.figshare.76911