Actin binding domains direct actin-binding proteins to different cytoskeletal locations-9

In and the localization examined. In each case, the results obtained were similar to the localization found when probes were expressed in wild-type cells. GFP-FLN maintains its cortical localization in the double mutant while GFP-αA is found in new protrusions but not in the cortex (Panels A and C). The same results were found for the ABD's of both proteins (Panels B and D).Copyright information:Taken from "Actin binding domains direct actin-binding proteins to different cytoskeletal locations"http://www.biomedcentral.com/1471-2121/9/10BMC Cell Biology 2008;9():10-10.Published online 13 Feb 2008PMCID:PMC2275727.