Additional file 2: of Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes

Additional file 2: of Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes

Figure S1. Effect of siRNAs or DNA expression plasmids transfections in C-MSCs. Figure S2. MSCs cultured on 2D plastic culture plate maintained YAP/TAZ activity. Figure S3. High YAP/TAZ activity in subconfluent MSCs cultured on a 2D plastic plate regulates the cell lineage into osteogenesis but not...

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Hauptverfasser: Komatsu, Nao, Mikihito Kajiya, Souta Motoike, Takewaki, Manabu, Horikoshi, Susumu, Iwata, Tomoyuki, Ouhara, Kazuhisa, Takeda, Katsuhiro, Matsuda, Shinji, Fujita, Tsuyoshi, Kurihara, Hidemi
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Sprache:eng
Schlagworte:
Biochemistry
Biological Sciences not elsewhere classified
Cell Biology
Developmental Biology
FOS: Biological sciences
FOS: Health sciences
Hematology
Infectious Diseases
Medicine
Molecular Biology
Physiology
Space Science
Virology
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Zusammenfassung:Figure S1. Effect of siRNAs or DNA expression plasmids transfections in C-MSCs. Figure S2. MSCs cultured on 2D plastic culture plate maintained YAP/TAZ activity. Figure S3. High YAP/TAZ activity in subconfluent MSCs cultured on a 2D plastic plate regulates the cell lineage into osteogenesis but not adipo/chondrogenesis. Figure S4. Disruption of F-actin integrity by ROCK inhibitor and acto-myosin inhibitor abrogates the TAZS89A-induced positive feedback loop for in C-MSCs. (ZIP 6647Â kb)
DOI:10.6084/m9.figshare.7439900