Additional file 8: of Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors
Figure S7. Histological features in RELA-negative/YAP1-negative supratentorial ependymoma cases. EP3 (EP300-BCORL1 fusion-positive) exhibits typical findings of anaplastic ependymoma, including hypercellularity, perivascular pseudorosettes (a), calcification (arrows, b) and high MIB-1 labeling index...
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Zusammenfassung: | Figure S7. Histological features in RELA-negative/YAP1-negative supratentorial ependymoma cases. EP3 (EP300-BCORL1 fusion-positive) exhibits typical findings of anaplastic ependymoma, including hypercellularity, perivascular pseudorosettes (a), calcification (arrows, b) and high MIB-1 labeling index (c). In EP57 (FOXO1-STK24 fusion-positive), perivascular pseudorosettes (d), calcification (arrows, e), microcyst formation (e), vacuolated cells (f), GFAP-positive cells (g), EMA positive reaction (h) and low MIB-1 labeling index (i) were observed. (TIF 58932 kb) |
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DOI: | 10.6084/m9.figshare.7422578 |