Additional file 8: of Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors

Figure S7. Histological features in RELA-negative/YAP1-negative supratentorial ependymoma cases. EP3 (EP300-BCORL1 fusion-positive) exhibits typical findings of anaplastic ependymoma, including hypercellularity, perivascular pseudorosettes (a), calcification (arrows, b) and high MIB-1 labeling index...

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Hauptverfasser: Fukuoka, Kohei, Yonehiro Kanemura, Shofuda, Tomoko, Fukushima, Shintaro, Yamashita, Satoshi, Narushima, Daichi, Kato, Mamoru, Honda-Kitahara, Mai, Ichikawa, Hitoshi, Kohno, Takashi, Sasaki, Atsushi, Hirato, Junko, Hirose, Takanori, Komori, Takashi, Kaishi Satomi, Yoshida, Akihiko, Yamasaki, Kai, Nakano, Yoshiko, Takada, Ai, Taishi Nakamura, Takami, Hirokazu, Matsushita, Yuko, Tomonari Suzuki, Nakamura, Hideo, Makino, Keishi, Sonoda, Yukihiko, Ryuta Saito, Teiji Tominaga, Matsusaka, Yasuhiro, Kobayashi, Keiichi, Nagane, Motoo, Furuta, Takuya, Nakada, Mitsutoshi, Narita, Yoshitaka, Hirose, Yuichi, Ohba, Shigeo, Wada, Akira, Shimizu, Katsuyoshi, Kurozumi, Kazuhiko, Date, Isao, Fukai, Junya, Miyairi, Yousuke, Kagawa, Naoki, Atsufumi Kawamura, Yoshida, Makiko, Nishida, Namiko, Wataya, Takafumi, Yamaoka, Masayoshi, Tsuyuguchi, Naohiro, Uda, Takehiro, Takahashi, Mayu, Yoshiteru Nakano, Akai, Takuya, Izumoto, Shuichi, Nonaka, Masahiro, Yoshifuji, Kazuhisa, Kodama, Yoshinori, Mano, Masayuki, Ozawa, Tatsuya, Ramaswamy, Vijay, Taylor, Michael, Ushijima, Toshikazu, Shibui, Soichiro, Yamasaki, Mami, Arai, Hajime, Sakamoto, Hiroaki, Nishikawa, Ryo, Ichimura, Koichi
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Zusammenfassung:Figure S7. Histological features in RELA-negative/YAP1-negative supratentorial ependymoma cases. EP3 (EP300-BCORL1 fusion-positive) exhibits typical findings of anaplastic ependymoma, including hypercellularity, perivascular pseudorosettes (a), calcification (arrows, b) and high MIB-1 labeling index (c). In EP57 (FOXO1-STK24 fusion-positive), perivascular pseudorosettes (d), calcification (arrows, e), microcyst formation (e), vacuolated cells (f), GFAP-positive cells (g), EMA positive reaction (h) and low MIB-1 labeling index (i) were observed. (TIF 58932 kb)
DOI:10.6084/m9.figshare.7422578