Additional file 1: of GRIPT: a novel case-control analysis method for Mendelian disease gene discovery

Additional file 1: of GRIPT: a novel case-control analysis method for Mendelian disease gene discovery

Table S1. The sensitivity and specificity of GRIPT with CADD and other tests under the AR and AD models. Table S2. Benchmark on 400 randomly selected known disease genes. Table S3. Test the effect of the patient cohort sample size. Table S4. Test the effect of population stratification in cohorts. T...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Jun, Zhao, Li, Wang, Xia, Chen, Yong, Xu, Mingchu, Soens, Zachry, Ge, Zhongqi, Wang, Peter, Wang, Fei, Chen, Rui
Format: Dataset
Sprache:eng
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Biological Sciences not elsewhere classified
Computational Biology
FOS: Biological sciences
Genetics
Mathematical Sciences not elsewhere classified
Medicine
Neuroscience
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Zusammenfassung:Table S1. The sensitivity and specificity of GRIPT with CADD and other tests under the AR and AD models. Table S2. Benchmark on 400 randomly selected known disease genes. Table S3. Test the effect of the patient cohort sample size. Table S4. Test the effect of population stratification in cohorts. Table S5. Test the effect of variant frequency filtering. Table S6. Test the effect of the control cohort size. Table S7. The performance of detecting genes with modest-effect variants. (XLSX 111 kb)
DOI:10.6084/m9.figshare.7386539