Additional file 6: of Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings

JAM-A overexpression is insufficient to improve cell viability following short-term treatment with HER2-targeted drugs. MDA-MB-231 cells overexpressing full-length human JAM-A (JAM+) or a pcDNA3 empty vector control (EV) were treated for 3 days in serum-free medium with the indicated concentrations...

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Hauptverfasser: Leech, Astrid, Vellanki, Sri HariKrishna, Rutherford, Emily, Keogh, Aoife, Jahns, Hanne, Hudson, Lance, O’Donovan, Norma, Sabri, Siham, Abdulkarim, Bassam, Sheehan, Katherine, Kay, Elaine, Young, Leonie, Hill, Arnold, Smith, Yvonne, Hopkins, Ann
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