Additional file 4: of Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion

Decreased proliferation of nuclear stained GFP-Sox2 reporter cells at 72 h of treatment. Percentage total cell growth of GFP-Sox2 reporter cells at 72 h of treatment with PBS or progranulin (PGRN) (1 μg/ml). Left bar plots demonstrate nuclear-stained cells with NucBlue and right bar plot demonstrate...

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Hauptverfasser: Rhost, Sara, Éamon Hughes, Harrison, Hannah, Svanheidur Rafnsdottir, Jacobsson, Hanna, Gregersson, Pernilla, Magnusson, Ylva, Fitzpatrick, Paul, Andersson, Daniel, Berger, Karoline, Ståhlberg, Anders, Landberg, Göran
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