Additional file 4: of Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion

Decreased proliferation of nuclear stained GFP-Sox2 reporter cells at 72 h of treatment. Percentage total cell growth of GFP-Sox2 reporter cells at 72 h of treatment with PBS or progranulin (PGRN) (1 μg/ml). Left bar plots demonstrate nuclear-stained cells with NucBlue and right bar plot demonstrate unstained GFP-Sox2 reporter cells. (TIFF 110 kb)