Varied capacity of C-terminal BRCA1 variants to form foci in response to DNA damage

Varied capacity of C-terminal BRCA1 variants to form foci in response to DNA damage

Copyright information:Taken from "Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?"http://breast-cancer-research.com/content/9/6/R82Breast Cancer Research : BCR 2007;9(6):R82-R82.Published online 26 Nov 2007PMCID:PMC2...

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Hauptverfasser: Lovelock, Paul K, Spurdle, Amanda B, Myth TS Mok, Farrugia, Daniel J, Lakhani, Sunil R, Healey, Sue, Arnold, Stephen, Buchanan, Daniel, KConFab Investigators, Couch, Fergus J, Beric R Henderson, Goldgar, David E, Tavtigian, Sean V, Chenevix-Trench, Georgia, Brown, Melissa A
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Sprache:eng
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Molecular Biology
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Zusammenfassung:Copyright information:Taken from "Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?"http://breast-cancer-research.com/content/9/6/R82Breast Cancer Research : BCR 2007;9(6):R82-R82.Published online 26 Nov 2007PMCID:PMC2246181. Post-ionising radiation (IR) nuclear foci formation in cells co-transfected with the nuclear chaperone BARD1. Summary of nuclear foci formation data in untreated cells and cells treated with IR. UV, unclassified variant; WT, wild-type.
DOI:10.6084/m9.figshare.72683