The 3' untranslated region of human contains regulatory elements affecting transcript stability-6

Copyright information:Taken from "The 3' untranslated region of human contains regulatory elements affecting transcript stability"http://www.biomedcentral.com/1471-2199/8/111BMC Molecular Biology 2007;8():111-111.Published online 3 Dec 2007PMCID:PMC2222623.ol. Regions of at least 100 bp with identity greater than 70% are indicated in pink. The plots refer to the human 3'-UTR sequence (UTRdb ID: 3HSA086450). The position of the predicted regulatory elements is indicated. B) Multiple alignment of the last portion of human (Hs.), mouse (Mm.), rat (Rn.) and zebrafish (Dr.) 3'-UTR. Stars represent fully conserved positions; the best ARE consensus is boxed in gray, the polyA sites are in bold. C) Representation of the most stable secondary structure of the human 3'-UTR as predicted by the Sfold algorithm. The magnification shows the loop (arrow) corresponding to the ARE with the best consensus (nt 2659–2671).