Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein-1

Copyright information:Taken from "Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein"http://www.virologyj.com/content/4/1/123Virology Journal 2007;4():123-123.Published online 20 Nov 2007PMCID:PMC2211469.ce of 90%POPC:10%POPG (filled squares). Spectroscopic analysis revealed that each peptide possessed the characteristic minima at 208 nm and 222 nm indicating α-helical character. (a) LLP-1 labeled with NBD; (b) LLP-2 labeled with NBD; (c) LLP-3; (d) LLP-1D labeled with NBD. (e) The percent α-helicity was calculated from the CD spectroscopy curves in figure a-d for each peptide using the following formula: Θ/(1–2.5/n)(40,000), where n = the number of residues present in the peptide.