The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation-6

S), LY294002 or CNP + LY294002. Bone growth measurements showed increased bone growth in the CNP treatment, and no significant difference between the LY294002 and CNP+LY294002. (B) E 15.5 tibiae treated for 6 days with the treatments mentioned above, were fixed, embedded, sectioned and stained with H&E. The length of hypertrophic zone was increased in the CNP treatment compared to control, decreased in the LY294002 treatment and similar between LY294002 and CNP+LY294002Copyright information:Taken from "The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation"http://www.biomedcentral.com/1471-213X/8/40BMC Developmental Biology 2008;8():40-40.Published online 11 Apr 2008PMCID:PMC2329617.