An AICD-based functional screen to identify APP metabolism regulators-0

Copyright information:Taken from "An AICD-based functional screen to identify APP metabolism regulators"http://www.molecularneurodegeneration.com/content/2/1/15Molecular Neurodegeneration 2007;2():15-15.Published online 24 Aug 2007PMCID:PMC2071909.n (ADAM 10, ADAM17, Ubiquilin 1) or knock-...

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Hauptverfasser:	Zhang, Can, J Khandelwal, Preeti, Chakraborty, Ranjita, L Cuellar, Trinna, Sarangi, Srikant, A Patel, Shyam, P Cosentino, Christopher, O'Connor, Michael, C Lee, Jeremy, E Tanzi, Rudolph, J Saunders, Aleister
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Sprache:	eng
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Zusammenfassung:	Copyright information:Taken from "An AICD-based functional screen to identify APP metabolism regulators"http://www.molecularneurodegeneration.com/content/2/1/15Molecular Neurodegeneration 2007;2():15-15.Published online 24 Aug 2007PMCID:PMC2071909.n (ADAM 10, ADAM17, Ubiquilin 1) or knock-down (ADAM 10, ADAM17, Ubiquilin 1) mediated modulation of AICD-Gal4 levels we plotted the average fold change in AICD-Gal4 levels versus the average fold change in AICD-Gal4 mediated luciferase activity. For transient over-expression, luciferase activity and AICD-Gal4 levels were normalized to transfection efficiency by Renilla luciferase activity assays. The line is represents the least squares linear regression to this data.
DOI:	10.6084/m9.figshare.65110