Analysis identifies less conserved sequences that are also part of conserved sequence blocks

Copyright information:Taken from "-Decoder discovers constellations of conserved DNA sequences shared among tissue-specific enhancers"http://genomebiology.com/2007/8/5/R75Genome Biology 2007;8(5):R75-R75.Published online 9 May 2007PMCID:PMC1929141. The following species were used to produce an the 800 bp stripe 1 enhancer [18]: (reference sequence), , , , , , , , and . was not included in the analysis due to lack of sequence co-linearity detected with prints. Invariant MCSs, shared by all species used to generate the , are identified with uppercase black-colored letters. A of the enhancer with one of its 10 bp CSBs (blue highlight) revealed that it is repeated two additional times in the less conserved inter-block sequences (lowercase yellow highlighted sequences). Note that the underlined sequence in this CSB is the core DNA-binding sequence for the Tramtrack transcription factor.