Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the locus-1

Copyright information:Taken from "Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the locus"http://www.biomedcentral.com/1471-213X/7/69BMC Developmental Biology 2007;7():69-69.Published online 18 Jun 2007PMCID:PMC1906761.ression. Black arrows in (A-I) point to the third pharyngeal pouch. White arrows in (J-L) indicate the -negative parathyroid region of the primordium. For sagittal sections, ventral is left and anterior is up. For transverse sections, dorsal is up. A, B, Lateral views of E10.5 (A) and ;R26R(B) whole embryos, and D, E, coronal sections through E10.5 (D) and ;R26R(E) embryos showing no expression in the third pharyngeal pouch. G, H, Lateral views of E11.5 (G) and ;R26R(H) embryos showing expression only in the developing thymus primordium. J, K, Sagittal sections through E11.5 embryo (J) and E11.5 ;R26Rembryo (K) showing expression restricted to the ventral thymus domain of the 3pouch-derived organ primordium. M, Sagittal section through E12.5 thymus primordium. N, Transverse section through E12.5 ;R26Rthymus primordium. O, Transverse section through E12.5 thymus showing hybridization for mRNA. P, Section through E16.5 thymus. Q, R, Sections through E16.5 (Q) and newborn (R) ;R26Rthymi showing more intense staining in the prospective medullary regions. c = cortex, m = medulla.