Isolation of terpenoid isolated from Sarang Semut (Myrmecodia pendans), and its performance in the inhibition and eradication of formation of Streptococcus mutans biofilm

This dataset contains 21 data tables and graphs relating to the determination of a terpenoid structure, isolated from Sarang Semut (Myrmecodia pendans) and its potential forinhibition and eradication of formation of Streptococcus mutans biofilm.Files are in openly accessible .png image format and .xlsx format than be accessed via MS Excel or open office software.Background: the related publication describes the use of compounds isolated from Myrmecodia pendans in preventing Streptococcus mutans ATCC 25175 biofilm formation, a cause of dental caries. Myrmecodia pendans are native plants from Papua with empirically-reported uses as natural remedies for tumors, gout, diarrhea, and fever. Methodology: M. pendans was extracted with ethyl acetate using a Soxhlet extractor. The extract then separated and purified with the chromatography method to isolate the compound. The structure of the active compound was then characterized using the UV, IR, NMR, and MS spectrometers. The compounds obtained were induced into S. mutans biofilms to determine the MBIC and MBEC values.Supporting_Data_Meirina_(1).xlsx - numerical data underpinning MBEC values for supporting data_meirina (12) - supporting data_meirina (16) belowSupporting_Data_Meirina_(2).xlsx - numerical data underpinning MBIC values for supporting data_meirina (17) - supporting data_meirina (18) belowSupporting_Data_Meirina_(3).xlsx - numerical data involved in generating MIC values for supporting data_meirina (11) belowsupporting data_meirina (1).png - image of Sarang senut plant (a), split in the middle (b) and cut into small pieces (c)supporting data_meirina (2).png - TLC chromatogram using G60 F254 silica gel plate of 1-11 fraction with n-hexane-ethyl-acetate (3:7, v/v) on the UV λ 254 nm.Separation and purification of M. pendans bulb ethyl acetate extract was done by TLC.-Files supporting data_meirina 3-10:Determination of the structure of compound 1 was performed by analyzing the 1H-NMR,13C-NMR, HMQC, DEPT 135°, 1H-1H COSY and HMBC spectrum with a 500 MHz FT-NMR spectrometer (ECA 500 JOEL variant, Japan) The IR spectrum of the compound was determined by FT-IR Perkin Elmer Spectrum One spectrometer (Buckinghamshire, UK).Confirmation of the conjectural structure of compound 1 was determined using the mass spectroscopy (ES-MS Spectrometer, UPLC Type MS / MS TQD, Waters). supporting data_meirina (3).png - IR spectrum of Compound 1 in KBr platesupporting data_meirina (4).png - C-NMR Spectrum of Compound 1 (125 MH