Mitochondrial genome mutations in 13 subunits of respiratory chain complexes in Chinese Han and Mongolian hypertensive individuals

Mitochondrial genome mutations in 13 subunits of respiratory chain complexes in Chinese Han and Mongolian hypertensive individuals

Mitochondrial DNA (mtDNA) mutations are associated with cardiovascular disease, including hypertension (HTN). Here we performed a genetic and molecular analysis of 13 mtDNA-encoded subunits of respiratory chain complexes in 100 Chinese Han and 80 Mongolian HTN cases, and 100 Han and 42 Mongolian nor...

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Ying, Chen, Xi, Li, Haide, Zhu, Chao, Li, Yang, Liu, Yuqi
Format: Dataset
Sprache:eng
Schlagworte:
Biochemistry
FOS: Biological sciences
FOS: Sociology
Genetics
Medicine
Science Policy
Sociology
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Zusammenfassung:Mitochondrial DNA (mtDNA) mutations are associated with cardiovascular disease, including hypertension (HTN). Here we performed a genetic and molecular analysis of 13 mtDNA-encoded subunits of respiratory chain complexes in 100 Chinese Han and 80 Mongolian HTN cases, and 100 Han and 42 Mongolian normotension subjects. The total cholesterol of the Mongolian normotensive subjects was higher than that of the Han normotensive group (p 
DOI:10.6084/m9.figshare.5633737