Integrated proteogenomic analysis of laser capture microdissected breast tumors (AACR 2017 Annual Meeting)

To investigate the proteogenomic landscape of breast cancer subtypes by integrating comprehensive transcriptomic, proteomic, and phosphoproteomic data, in a cohort with a substantial representation of African Americans, with a secondary objective of identifying druggable proteins that are differenti...

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Hauptverfasser: Omics, PNNL, Sridhara, Viswanadham, Liu, Tao, Gritsenko, Marina A., Sturtz, Lori A., Kovatich, Albert J., Petyuk, Vladislav A., Deyarmin, Brenda, McDermott, Jason E., Shukla, Anil K., Moore, Ronald J., Monroe, Matthew E., Webb-Robertson, Bobbie-Jo M., Hooke, Jeffrey A., Fantacone-Campbell, Leigh, Kumar Raj Kumar, Praveen, Kvecher, Leonid, Liu, Jianfang, Kane, Jennifer, Melley, Jennifer, Somiari, Stella, Iida, Joji, Benz, Stephen C., Golovato, Justin, Rabizadeh, Shahrooz, Soon-Shiong, Patrick, Smith, Richard D., J. Mural, Richard, D. Shriver, Craig, Hu, Hai, Rodland, Karin D.
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Sprache:eng
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Zusammenfassung:To investigate the proteogenomic landscape of breast cancer subtypes by integrating comprehensive transcriptomic, proteomic, and phosphoproteomic data, in a cohort with a substantial representation of African Americans, with a secondary objective of identifying druggable proteins that are differentially expressed in specific subtypes.
DOI:10.6084/m9.figshare.5153884