Detection of the autoantibodies to citrullinated or non-citrullinated F-actin capping protein α-1 subunit (CapZα-1) by enzyme-linked immunosorbent assay (ELISA)

Copyright information:Taken from "Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach"Arthritis Research & Therapy 2006;8(6):R175-R175.Published online 27 Nov 2006PMCID:PMC1794520. The autoantibodies to citrullinated or non-citrullinated CapZα-1 were detected by ELISA in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) , systemic lupus erythematosus (SLE) , and in healthy donors (age- and gender-matched to RA, OA, or SLE groups). The dotted line indicates the cutoff point for positive reaction of 100 binding units. Serum samples diluted at 1:400 were used. The numbers in square brackets indicate the numbers of the antibody-positive serum samples/the numbers of the tested serum samples in each category. The numbers in parenthesis indicate percentages of the antibody-positive serum samples in each category.