Intracellular concentrations of mono-, di- and triphosphate nucleotides (AXP, CXP, GXP, UXP) in micromoles per gram of dry weight (μmol/g DW) following 5

Copyright information:Taken from "When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation"Molecular Systems Biology 2006;2():49-49.Published online 12 Sep 2006PMCID:PMC1681515.Copyright © 2006, EMBO and Nature Publishing Group6 mM glucose pulse. () ATP, () ADP, () AMP, () e-charge defined as the ratio (ATP+0.5 ADP)/(ATP+ADP+AMP), () ΣAXP, () ΣGXP, () ΣCXP, () ΣUXP and () possible adenine nucleotide utilization. ATP, ADP, AMP and cAMP comprise the adenine nucleotide (AXP) pool in which any reaction between them does not cause any depletion in the pool size. Outside the circle are the reactions that are consuming the adenine moiety of the AXP. Adapted from . () Theoretical distribution of AXP based on change in the synthesis rate owing to growth acceleration (from μ=0.05/h to μ=0.45/h). Detailed calculations are provided in . The data plotted originate from at least two independent pulse experiments.