Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation-2

Copyright information:Taken from "Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation"BMC Neuroscience 2006;7():55-55.Published online 14 Jul 2006PMCID:PMC1540436.istochemistry with a specific antibody to the neuronal marker NeuN () or by TUNEL-histochemistry of adjacent sections (). The overall cellular morphology of the TUNEL sections is revealed by DAPI nuclear stain (). The panels represent a 4-fold magnification of the respective panels . The evident destruction of the cortical tissue in brain-injured wild-type mice (upper panels) appears to be structurally preserved in -/- mice (bottom panels). The data shown here are highly reproducible in all tissue sections and animals assessed. Original magnifications: 100× (), 400× ().