Clustered image map (CIM) relating drug activity to gene expression in lung cancer cell lines using GeneChip – Experiment 2

Copyright information:Taken from "Anticancer drug clustering in lung cancer based on gene expression profiles and sensitivity database"BMC Cancer 2006;6():174-174.Published online 30 Jun 2006PMCID:PMC1533844. (A) all lung cancer cell lines, (B) NSCLC. The cluster trees of drugs (y axis) an...

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Hauptverfasser: Gemma, Akihiko, Li, Cai, Sugiyama, Yuka, Matsuda, Kuniko, Seike, Yoko, Kosaihira, Seiji, Minegishi, Yuji, Rintaro Noro, Nara, Michiya, Seike, Masahiro, Yoshimura, Akinobu, Shionoya, Aki, Kawakami, Akiko, Ogawa, Naoki, Uesaka, Haruka, Kudoh, Shoji
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Sprache:eng
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Zusammenfassung:Copyright information:Taken from "Anticancer drug clustering in lung cancer based on gene expression profiles and sensitivity database"BMC Cancer 2006;6():174-174.Published online 30 Jun 2006PMCID:PMC1533844. (A) all lung cancer cell lines, (B) NSCLC. The cluster trees of drugs (y axis) and gene expression (x axis) were shown in the CIM. Each block of colors represents correlations between clusters of genes and drugs; red (high positive correlation) and blue (negative correlation). In this analysis, gemcitabine belonged to an isolated cluster (Fig. 3A,B). GEM; gemcitabine, PAC; paclitaxel, DOC; docetaxel, VIN; vinorelbine
DOI:10.6084/m9.figshare.42119