Increased trabecular bone formation in female transgenic mice

Copyright information:Taken from "Leaky ribosomal scanning in mammalian genomes: significance of histone H4 alternative translation "Nucleic Acids Research 2005;33(4):1298-1308.Published online 1 Mar 2005PMCID:PMC552952.© The Author 2005. Published by Oxford University Press. All rights reserved Dynamic histomorphometric analysis, based on fluorescing calcein labels, in the distal femoral metaphysical trabecular bone of 8- and 17-week-old female (–) and male (–) mice. (A and D) mineralizing perimeter (Min.Peri); (B and E) mineral appositional rate (MAR); (C and F) bone formation rate (BFR). (–) Fluorescent images from calcein-labeled distal femoral metaphyses of a 17-week-old wild-type (G) and transgenic (H) females with median BFR values. Data are mean ± SEM. Shaded bars, transgenic mice; solid bars, wild-type mice; < 0.05.