Description and analysis of the contacts between gentamicin C1A and the RNA fragment

Copyright information:Taken from "Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding"Nucleic Acids Research 2005;33(17):5677-5690.Published online 7 Oct 2005PMCID:PMC1251667.© The Author 2005. Published by Oxford University Press. All rights reserved Structure adopted by the gentamicin C1A molecule inside the A site of the duplex. Ring numbers (I–III) and atom names are specified. The numbering is used for the RNA atoms, and ‘W’ stands for water molecule. Hydrogen bonds are shown as dashed lines. Conserved contacts between gentamicin C1A and the minimal A site are shown in red. Atomic details of the contacts involving each base pair of the minimal A site interacting with gentamicin C1A.