Organization of and thioredoxin reductase (TR-Se) genes and structures of their SECIS elements

Copyright information:Taken from "Nematode selenoproteome: the use of the selenocysteine insertion system to decode one codon in an animal genome?"Nucleic Acids Research 2005;33(7):2227-2238.Published online 20 Apr 2005PMCID:PMC1083425.© The Author 2005. Published by Oxford University Press. All rights reserved () TR-Se genes are shown with boxes indicating exons and lines connecting boxes representing introns. Filled boxes show coding regions, and open boxes represent untranslated regions within exons. The locations of initiator ATG codons, Sec-encoding TGA codons, and terminator signals in the and genes are indicated. Gray boxes indicate the location of SECIS elements in 3′-UTRs. Upper and lower row numbers correspond to the beginning and the end of each exon, respectively. The TR-Se gene sequence is located in a contig cb25.fpc0143 from assembly cb25.agp8 (gi:22417497; CAE61785). The TR-Se gene is located on chromosome IV (accession no. AF148217). () SECIS elements in and . The quartet of non-Watson–Crick interacting nucleotides, an unpaired G preceding the quartet, and an unpaired AA motif in the apical bulge are shown in bold.