Condensation of , nicked-DNA and a 21mer duplex by hexammine cobalt chloride, as monitored by light scattering

Copyright information:Taken from "Condensation of oligonucleotides assembled into nicked and gapped duplexes: potential structures for oligonucleotide delivery"Nucleic Acids Research 2005;33(1):143-151.Published online 07 Jan 2005PMCID:PMC546144.© 2005, the authors © For each data point shown, DNA concentration was 7.5 μM in base pair (5 mM Bis-Tris, 50 μM EDTA, pH 7.0). Light-scattering intensities shown are averages from measurements taken over a 5 min period. : and nicked-DNA scattering intensities, as a function of hexammine cobalt chloride concentration, normalized to maximum observed intensity. : nicked-DNA condensation occurs at a lower hexammine cobalt chloride concentration than .