Fold change distribution for genes differentially expressed in pre-inflamed joints, in paws with acute and chronic arthritis, in comparison with gene expression in normal paws of naive BALB/cmice

Copyright information:Taken from "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation"Arthritis Research & Therapy 2004;7(2):R196-R207.Published online 14 Dec 2004PMCID:PMC1065315.Copyright © 2004 Adarichev et al.; licensee BioMed Central Ltd. Values indicate the number of genes that fall in the given range of expression. Negative numbers for expression levels indicate downregulation (e.g. a negative twofold change corresponds to downregulation to 0.5-fold). Spikes at ± 5-fold expression change represent the extremes of histogram when combining all genes with differential expression level greater than ± 5-fold. The Venn diagram (bottom) indicates the number of overlapping genes that were differentially expressed in pre-inflamed and arthritic joints.