Expression of CD69 and human leucocyte antigen (HLA) DR by B8-RAKFKQLL-specific T cells in peripheral blood and synovial fluid from patient RhA7

Copyright information:Taken from "Specificity of T cells in synovial fluid: high frequencies of CD8 T cells that are specific for certain viral epitopes"Arthritis Research 2000;2(2):154-164.Published online 7 Feb 2000PMCID:PMC17809.Copyright © 2000 Current Science Ltd Samples of peripheral blood mononuclear cells (dashed lines) and synovial fluid mononuclear cells (continuous lines) were stained with the B8/RAKFKQLL tetramer, with anti-CD8 and with monoclonal antibodies specific for CD69 or HLA-DR; 200 000 live cells were analyzed, and expression of CD69 and HLA-DR by the populations of CD8+ B8/RAKFKQLL tetramer reactive cells is shown. FITC, fluorescein isothiocyanate