(Chagas' disease agent) reduces HIV-1 replication in human placenta-2

Ith VSV-G pseudotyped HIV-1 (V) (100 ng p24/2 × 10cells per well) alone or in the presence of blood trypomastigotes (BT) (2 × 10parasites/2 × 10cells per well) or 24 h-supernatant of BT (BTSn). Cells were lysed and luciferase activity as an indicator of viral replication was read from cell lysates a...

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Hauptverfasser: Guillermina Laura Dolcini, Solana, María Elisa, Andreani, Guadalupe, Celentano, Ana María, Parodi, Laura María, Donato, Ana María, Elissondo, Natalia, Cappa, Stella Maris González, Giavedoni, Luis David, Peralta, Liliana Martínez
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Zusammenfassung:Ith VSV-G pseudotyped HIV-1 (V) (100 ng p24/2 × 10cells per well) alone or in the presence of blood trypomastigotes (BT) (2 × 10parasites/2 × 10cells per well) or 24 h-supernatant of BT (BTSn). Cells were lysed and luciferase activity as an indicator of viral replication was read from cell lysates at day 4 post-infection or coinfection. Results are expressed as relative light units per second (RLU/sec), presented as a percentage relative to VSV-G. The histogram in red corresponds to the % of infection with VSV-G (= 100%) and the histogram in white corresponds to the % of infection in the presence of BT. Results are representative of 3 independent experiments.Copyright information:Taken from "(Chagas' disease agent) reduces HIV-1 replication in human placenta"http://www.retrovirology.com/content/5/1/53Retrovirology 2008;5():53-53.Published online 1 Jul 2008PMCID:PMC2464605.
DOI:10.6084/m9.figshare.27505