(Chagas' disease agent) reduces HIV-1 replication in human placenta-1

with VSV-G pseudotyped HIV-1 (V) (100 ng p24/placental block) alone or in the presence of blood trypomastigotes (BT) (10parasites/placental block) or 24 h-supernatant of BT (BTSn). After infection or coinfection, tissue functionality of placental histocultures was analyzed by measuring total hCG sec...

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Hauptverfasser: Guillermina Laura Dolcini, Solana, María Elisa, Andreani, Guadalupe, Celentano, Ana María, Parodi, Laura María, Donato, Ana María, Elissondo, Natalia, Cappa, Stella Maris González, Giavedoni, Luis David, Peralta, Liliana Martínez
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Sprache:eng
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Zusammenfassung:with VSV-G pseudotyped HIV-1 (V) (100 ng p24/placental block) alone or in the presence of blood trypomastigotes (BT) (10parasites/placental block) or 24 h-supernatant of BT (BTSn). After infection or coinfection, tissue functionality of placental histocultures was analyzed by measuring total hCG secretion levels in histoculture supernatants by the chemiluminescence method at day 4 post-infection or coinfection. Results represent mean ± SD of duplicates and are representative of 5 independent experiments.Copyright information:Taken from "(Chagas' disease agent) reduces HIV-1 replication in human placenta"http://www.retrovirology.com/content/5/1/53Retrovirology 2008;5():53-53.Published online 1 Jul 2008PMCID:PMC2464605.
DOI:10.6084/m9.figshare.27504