Additional file 1 of Deciphering genetic and nongenetic factors underlying tumour dormancy: insights from multiomics analysis of two syngeneic MRD models of melanoma and leukemia

Additional file 1: Table S1. The following raw data were obtained: exome sequencing data, histone epigenetic marker data, transcriptomic gene expression data and proteomic MS data. a) Description of mutation types in the indicated genes in DA1-3b and B16-F1 cells. b) Multiomics data analysis from CNV, histones marks, and transcriptomic gene expression data for the indicated mutated genes in both MRD models. c) Percentages of the indicated mutated genes and the associated CNVs in the human AML and melanoma cohorts. d) Percent of the 50 most frequently mutated genes and the associated CNVs in the human AML and melanoma cohorts. The values are represented by a distinct colour gradient. For human melanoma samples, the results are represented according to the stage of disease progression, i.e., primary or metastatic tumours. The data were extracted from the public domain GDC portalversion 1.0. e) Proteomic MS analysis and resulting LFQ data in both MRD models. f) Multiomics data analysis of CNV, histones marks, and transcriptomic gene expression data for the indicated dysregulated proteins in the leukemia model. g) Multiomics data analysis of CNV, histones marks, and transcriptomic gene expression data for the indicated dysregulated proteins in a melanoma model. h) Multiomics data analysis of CNV, histones marks, and transcriptomic gene expression data for the 11 common dysregulated proteins in both MRD models