Additional file 3 of Inhibition of adenylyl cyclase by GTPase-deficient Gαi is mechanistically different from that mediated by receptor-activated Gαi
Additional file 3: Fig. S3. Preserved inhibitory function of Gαi1 in other investigated sites. HEK293 cells were transfected with QL-bearing Gαi1constructs and assayed as in Fig. 3B. The relative activities of the constitutively active mutants are expressed as a percentage of cAMP accumulation of Gα...
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| creator | Chung, Yin Kwan Chan, Ho Yung Lee, Tung Yeung Wong, Yung Hou |
| description | Additional file 3: Fig. S3. Preserved inhibitory function of Gαi1 in other investigated sites. HEK293 cells were transfected with QL-bearing Gαi1constructs and assayed as in Fig. 3B. The relative activities of the constitutively active mutants are expressed as a percentage of cAMP accumulation of Gαi1. Data shown are mean ± SEM (n=3). Bonferroni t test, p < 0.05; †, significant inhibition; #, significantly higher than the control; *, significantly lower than the control. |
| doi_str_mv | 10.6084/m9.figshare.26702605 |
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| subjects | Biochemistry Cancer Cell Biology Chemical Sciences not elsewhere classified FOS: Biological sciences FOS: Health sciences Genetics Infectious Diseases Microbiology Molecular Biology Neuroscience Pharmacology Physiology Virology |
| title | Additional file 3 of Inhibition of adenylyl cyclase by GTPase-deficient Gαi is mechanistically different from that mediated by receptor-activated Gαi |
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