Additional file 3 of Inhibition of adenylyl cyclase by GTPase-deficient Gαi is mechanistically different from that mediated by receptor-activated Gαi

Additional file 3: Fig. S3. Preserved inhibitory function of Gαi1 in other investigated sites. HEK293 cells were transfected with QL-bearing Gαi1constructs and assayed as in Fig. 3B. The relative activities of the constitutively active mutants are expressed as a percentage of cAMP accumulation of Gαi1. Data shown are mean ± SEM (n=3). Bonferroni t test, p < 0.05; †, significant inhibition; #, significantly higher than the control; *, significantly lower than the control.