Additional file 3 of Nelfinavir inhibition of Kaposi’s sarcoma-associated herpesvirus protein expression and capsid assembly

Supplementary Material 3. Fig. S3. Ultrastructural analyses of nelfinavir treated 5r219 cells. 5r219 cells were incubated with 20 µM nelfinavir for 72 h following induction. Whole cells were imaged by TEM. The panels show the nuclei (nuc) and cytoplasmic (cyto) regions of these cells. Electron dense aggregates were evident in the nuclei (white arrowheads). No mature or enveloped virions were observed in the cytoplasm of the nelfinavir treated cells. Scale bar = 2000 micron.