Additional file 5 of TBC1D5 reverses the capability of HIF-2α in tumor progression and lipid metabolism in clear cell renal cell carcinoma by regulating the autophagy

Additional file 5: Figure S5. Semi-quantification of oil-red staining. A. FIG3.G: lipid droplet accumulation in ccRCC cells was significantly decreased by TBC1D5 overexpression. B. FIG4.G: chloroquine promote lipid accumulation in ccRCC, rapamycin inhibit lipid accumulation in ccRCC, chloroquine reverse the inhibitory effect by TBC1D5 overexpression, while rapamycin is in synergy with TBC1D5 overexpression. C. FIG5.E: lipid accumulation in cells significantly reduced after HIF-2α knockdown, knockdown of TBC1D5 significantly increased lipid accumulation, knockdown of both HIF-2α and TBC1D5 can reverse the decreased lipid accumulation caused by knockdown of HIF-2α alone. *P