Additional file 8 of Clinical impact and in vitro characterization of ADNP variants in pediatric patients

Additional file 8 of Clinical impact and in vitro characterization of ADNP variants in pediatric patients

Additional file 8. Figure S3: Subcellular localization of ADNP mutant p.Y719X in HEK293T cells. Representative immunofluorescence images showing the expression of hADNP and hmut5/6 (c2157 C>A) and hmut7/8 (c2157 C>G) in HEK293T cells at low magnification. HA-ADNP (purple), anti-HA recognizes a...

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Bibliographische Detailangaben
Hauptverfasser: Ge, Chuanhui, Tian, Yuxin, Hu, Chunchun, Mei, Lianni, Li, Dongyun, Dong, Ping, Zhang, Ying, Li, Huiping, Sun, Daijing, Peng, Wenzhu, Xu, Xiu, Jiang, Yan, Xu, Qiong
Format: Bild
Sprache:eng
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FOS: Biological sciences
Genetics
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Zusammenfassung:Additional file 8. Figure S3: Subcellular localization of ADNP mutant p.Y719X in HEK293T cells. Representative immunofluorescence images showing the expression of hADNP and hmut5/6 (c2157 C>A) and hmut7/8 (c2157 C>G) in HEK293T cells at low magnification. HA-ADNP (purple), anti-HA recognizes an HA-tag fused to the N-terminus of ADNP. ADNP-C’ (red), anti-ADNP recognizes the C-terminus of ADNP. EGFP is expressed as a non-fusion protein on a plasmid that displays cell morphology (green). Nuclei were counterstained with DAPI (blue). Scale bar, 30 μm.
DOI:10.6084/m9.figshare.26671170