Additional file 2 of Evaluation of cerebrospinal fluid levels of synaptic vesicle protein, VAMP-2, across the sporadic Alzheimer’s disease continuum

Additional file 2 of Evaluation of cerebrospinal fluid levels of synaptic vesicle protein, VAMP-2, across the sporadic Alzheimer’s disease continuum

Additional file 2: Figure S2. Specificity analysis of VAMP-2 Simoa assay. (A)Recombinant VAMP-1, VAMP-2, VAMP-3 were serially diluted in sample diluent and measured in parallel with the VAMP-2 homebrew assay.  (B) Correlation of VAMP-2 CSF concentrations obtained with Simoa versus MRM [13] on a subs...

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Hauptverfasser: Goossens, Julie, Cervantes González, Alba, Dewit, Nele, Lidón, Laia, Fortea, Juan, Alcolea, Daniel, Lleó, Alberto, Belbin, Olivia, Vanmechelen, Eugeen
Format: Bild
Sprache:eng
Schlagworte:
Biochemistry
Biophysics
Cell Biology
Hematology
Mental Health
Neuroscience
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Zusammenfassung:Additional file 2: Figure S2. Specificity analysis of VAMP-2 Simoa assay. (A)Recombinant VAMP-1, VAMP-2, VAMP-3 were serially diluted in sample diluent and measured in parallel with the VAMP-2 homebrew assay.  (B) Correlation of VAMP-2 CSF concentrations obtained with Simoa versus MRM [13] on a subset (n=41) of the SPIN cohort. VAMP, vesicle-associated membrane protein; MRM, multiple reaction monitoring; ρ, Spearman rank correlation coefficient; CI, confidence interval.
DOI:10.6084/m9.figshare.26633553