Additional file 3 of Connexin-43 hemichannels orchestrate NOD-like receptor protein-3 (NLRP3) inflammasome activation and sterile inflammation in tubular injury

Additional file 3 of Connexin-43 hemichannels orchestrate NOD-like receptor protein-3 (NLRP3) inflammasome activation and sterile inflammation in tubular injury

Additional file 3: Figure 3. Peptide 5 protocol. (Panel a) Experimental design for the Cx43 hemichannel specific blocker Peptide5 (P5). Peptide5 was administered intraperitoneally twice a day for 9 days following UUO. All mice were sacrificed at day 10. (Panel b) Kidneys from wild type (WT) controls...

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Hauptverfasser: Roger, Elena, Chadjichristos, Christos E., Kavvadas, Panagiotis, Price, Gareth W., Cliff, Chelsy L., Hadjadj, Safia, Renciot, Jessy, Squires, Paul E., Hills, Claire E.
Format: Bild
Sprache:eng
Schlagworte:
Biochemistry
Biological Sciences not elsewhere classified
Cancer
Cell Biology
Developmental Biology
FOS: Biological sciences
FOS: Clinical medicine
Genetics
Immunology
Marine Biology
Medicine
Microbiology
Molecular Biology
Neuroscience
Pharmacology
Physiology
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Zusammenfassung:Additional file 3: Figure 3. Peptide 5 protocol. (Panel a) Experimental design for the Cx43 hemichannel specific blocker Peptide5 (P5). Peptide5 was administered intraperitoneally twice a day for 9 days following UUO. All mice were sacrificed at day 10. (Panel b) Kidneys from wild type (WT) controls and mice with or without Peptide5 injections were collected after 10 days of UUO for RNA extraction, renal morphometry and immunostainings.
DOI:10.6084/m9.figshare.26620552