Additional file 5 of Identifying primary and secondary MLH1 epimutation carriers displaying low-level constitutional MLH1 methylation using droplet digital PCR and genome-wide DNA methylation profiling of colorectal cancers

Additional file 5. Figure S4: “Circos” plots showing mean genomic hypomethylation and hypermethylation patterns in tumours of five reference CRC groups. For the MLH1 epimutation group, five primary and two secondary epimutation CRCs were combined in this analysis. Mean methylation values are shown p...

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Hauptverfasser: Joo, Jihoon E., Mahmood, Khalid, Walker, Romy, Georgeson, Peter, Candiloro, Ida, Clendenning, Mark, Como, Julia, Joseland, Sharelle, Preston, Susan, Graversen, Lise, Wilding, Mathilda, Field, Michael, Lemon, Michelle, Wakeling, Janette, Marfan, Helen, Susman, Rachel, Isbister, Joanne, Edwards, Emma, Bowman, Michelle, Kirk, Judy, Ip, Emilia, McKay, Lynne, Antill, Yoland, Hopper, John L., Boussioutas, Alex, Macrae, Finlay A., Dobrovic, Alexander, Jenkins, Mark A., Rosty, Christophe, Winship, Ingrid M., Buchanan, Daniel D.
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Sprache:eng
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Zusammenfassung:Additional file 5. Figure S4: “Circos” plots showing mean genomic hypomethylation and hypermethylation patterns in tumours of five reference CRC groups. For the MLH1 epimutation group, five primary and two secondary epimutation CRCs were combined in this analysis. Mean methylation values are shown per each CRC group.
DOI:10.6084/m9.figshare.26593871