Additional file 2 of The addition of arginine deiminase potentiates Mithramycin A-induced cell death in patient-derived glioblastoma cells via ATF4 and cytochrome C

Additional file 2 of The addition of arginine deiminase potentiates Mithramycin A-induced cell death in patient-derived glioblastoma cells via ATF4 and cytochrome C

Additional file 2: Figure S2. Senescence detection via activation of p16/p21/p53. Representative images of GBM cells (HROG05, HROG63) demonstrate an increase in p16, p21 and p53 after MitA-related treatment regimes. The cells were treated as indicated, fixed, permeabilized, and stained with p21 Waf1...

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Hauptverfasser: Linke, Charlotte, Freitag, Thomas, Riess, Christin, Scheffler, Jana Vanessa, del Moral, Katharina, Schoenwaelder, Nina, Fiedler, Tomas, Fiebig, Adina, Kaps, Philipp, Dubinski, Daniel, Schneider, Björn, Bergmann, Wendy, Classen, Carl Friedrich, Maletzki, Claudia
Format: Bild
Sprache:eng
Schlagworte:
Cancer
Cell Biology
Developmental Biology
FOS: Biological sciences
Genetics
Mathematical Sciences not elsewhere classified
Pharmacology
Space Science
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Zusammenfassung:Additional file 2: Figure S2. Senescence detection via activation of p16/p21/p53. Representative images of GBM cells (HROG05, HROG63) demonstrate an increase in p16, p21 and p53 after MitA-related treatment regimes. The cells were treated as indicated, fixed, permeabilized, and stained with p21 Waf1/Cip1 (12D1) rabbit mAb (Alexa 488 conjugate) [green], p16 antibody (JC8): sc-56330 Alexa 546 [orange] and Alexa Flour® 594 anti-p53 antibody [red] (scale bar: 50 μm).
DOI:10.6084/m9.figshare.26571517