Additional file 2 of Blood-based molecular and cellular biomarkers of early response to neoadjuvant PD-1 blockade in patients with non-small cell lung cancer

Supplementary Material 2: figure S2 Forest plots showing the standardized mean of gene expression difference between normal and tumor tissue as estimated from multiple studies (collected from LCE database). The leftmost column shows the included studies by the first author’s name and publication year and followed by the cohort size. The circles lined up in each column represent the effect estimates from individual studies and the very bottom circles show the pooled result for each gene as annotated. The size of each circle indicates the cohort size of individual study. The horizontal lines through the boxes illustrate the length of the 95% confidence interval in both positive and negative sides. Random-effects model was utilized to evaluate the overall effect as described by z-score and p value. v, versus; N, normal lung tissue; T, lung cancer tissue.